Found 27 matching trials
Dichloroacetate Kinetics, Metabolism and Toxicology N/A Dichloroacetate (DCA) is a product of water chlorination and a metabolite o...
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Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM) PHASE2 Conduct a multicenter, open label Phase IIA trial of oral DCA in 40 surgica...
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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The Safety and Efficacy of DCA for the Treatment of Brain Cancer PHASE2 Malignant gliomas, which include Glioblastoma multiforme (GBM), are the mos...
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University of Alberta Hospital
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Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors PHASE1 The purpose of this study is to evaluate the safety and tolerability of ora...
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University of Florida
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Pharmacotoxicology of Trichloroethylene Metabolites NA To establish the relationship between human MAAI haplotype and DCA and tyro...
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University of Florida Shands Hospital
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Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia PHASE2 OBJECTIVES: I. Determine the pharmacokinetics of sodium dichloroacetate (DC...
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University of California San Diego School of Medicine
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Role of Preoperative Carbohydrates Drinks, Dichloroacetate and Exercise on Postoperative Muscle Insulin Resistance PHASE4 The aim of the study is to investigate whether preoperative interventions s...
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University Hospitals Nottingham Queen's Medical Centre
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Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension PHASE1 Hypothesis: The small molecule and metabolic modulator Dichloroacetate (DCA...
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University of Alberta Hospital
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A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours PHASE1 Dichloroacetate (DCA) is a small molecule that has been used for years to t...
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Cross Cancer Institute
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Regulation of Brain Glucose Metabolism in Type 1 Diabetes EARLY_PHASE1 This is a prospective randomized placebo-controlled double-blind crossover ...
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Yale-New Haven Hospital
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